I-Carbapenem-resistant VIM Detection K-Set (Lateral Flow Assay) yinkqubo yokuvavanya i-immunochromatographic ejoliswe ekufumaneni umgangatho we-VIM-uhlobo lwe-carbapenemase kwiikholoni zebhaktheriya.Uvavanyo luvavanyo lwebhubhoratri yokusetyenziswa kwemithi enokuthi incede ekuxilongweni kweVIM-uhlobo lwe-carbapenem resistant strains.
Igama | Carbapenem-resistant VIM Detection K-Set (Lateral Flow Assay) |
Indlela | I-Lateral Flow Assay |
Uhlobo lwesampuli | Iikholoni zebhaktheriya |
Inkcazo | Iimvavanyo ezingama-25/ikhithi |
Ixesha lokubona | 10-15 imiz |
Izinto zokubhaqa | Carbapenem-resistant Enterobacteriaceae (CRE) |
Uhlobo lokufunyanwa | VIM |
Uzinzo | I-K-Set izinzile iminyaka emi-2 ku-2°C-30°C |
I-Carbapenem-resistant Enterobacteriaceae (CRE) yinxalenye yeqela leentsholongwane ezihlala emathunjini abanye abantu.Zinxulumene ne-E. coli, kodwa kuqhelekile ukuba ne-E. coli emathunjini akho nakwisitulo.Ingxaki yenzeka xa ezi ntsholongwane ziguquka kwaye zikwazi ukumelana namayeza okubulala iintsholongwane.Ezinye i-CRE zixhathisa amayeza amaninzi kangangokuba awanyangeki, kwaye ukuya kuthi ga kwisiqingatha sezigulana ezosulelekileyo zinokufa.Oku kuxhalabisa kakhulu kuba i-carbapenems yayidla ngokuba yenye yamayeza okubulala iintsholongwane anokunyanga ngempumelelo enye i-Enterobacter “superbugs.”
Iindlela eziqhelekileyo ezithathwayo ukulawula ukusasazeka kwe-CRE:
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Yiyo loo nto ukuchwetheza kwangoko kwe-CRE subtypes kubalulekile kulawulo lwe-CRE lweklinikhi.Iikiti zovavanyo ze-CRE ezikhawulezayo nezichanekileyo zinokunceda ngomyalelo wonyango, ulawulo lwesigulane, ngaloo ndlela kuncitshiswe ukwanda kwesantya sokuxhathisa amayeza okubulala iintsholongwane.
I-Carbapenemase luhlobo lwe-β-lactamase olunokuthi ubuncinane lube ne-hydrolyze imipenem okanye i-meropenem, kuquka i-A, B, D iintlobo ezintathu.Kule ntlobo, i-Class B i-metallo-β-lactamases (MBLs), kuquka i-carbapenemases efana ne-IMP, i-VIM kunye ne-NDM, eyayifumaneka kakhulu kwi-Pseudomonas aeruginosa, i-Acinetobacteria kunye ne-Enterobacteriaceae bacteria.I-Verona Integron-encoded Metallo-beta-lactamase (VIM) yeyona carbapenemase idibana rhoqo kwi-P. aeruginosa3.Phakathi kwezinto ezahlukeneyo, i-VIM-2 metallo-beta-lactamase ibonisa usasazo olubanzi lwejografi, kubandakanywa nelizwekazi laseYurophu.
Umzekelo | Inkcazo | Ikhowudi yemveliso |
I-CPV-01 | Iimvavanyo ezingama-25/ikhithi | I-CPV-01 |