Carbapenem-resistant IMP Fuction K-Set (Lateral Flow Assay)

Uvavanyo olukhawulezayo lwe-IMP ye-CRE ngaphakathi kwe-10-15 min

Izinto zokubhaqa	Carbapenem-resistant Enterobacteriaceae (CRE)
Indlela yokusebenza	I-Lateral Flow Assay
Uhlobo lwesampuli	Iikholoni zebhaktheriya
Iinkcukacha	Iimvavanyo ezingama-25/ikhithi
Ikhowudi yemveliso	CPI-01

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iithegi zeMveliso

Intshayelelo yeMveliso

I-Carbapenem-resistant IMP Detection K-Set (Lateral Flow Assay) yinkqubo yovavanyo lwe-immunochromatographic ejoliswe ekufumaneni umgangatho we-IMP-uhlobo lwe-carbapenemase kwiikholoni zebhaktheriya.Uvavanyo luvavanyo lwebhubhoratri yokusetyenziswa kwemithi enokuthi incede ekuxilongweni kwe-IMP-uhlobo lwe-carbapenem resistant strains.

Carbapenem-resistant NDM Detection K-Set (Lateral Flow Assay) 1

Iimpawu

Igama	Carbapenem-resistant IMP Fuction K-Set (Lateral Flow Assay)
Indlela	I-Lateral Flow Assay
Uhlobo lwesampuli	Iikholoni zebhaktheriya
Inkcazo	Iimvavanyo ezingama-25/ikhithi
Ixesha lokubona	10-15 imiz
Izinto zokubhaqa	Carbapenem-resistant Enterobacteriaceae (CRE)
Uhlobo lokufunyanwa	IMP
Uzinzo	I-K-Set izinzile iminyaka emi-2 ku-2°C-30°C

Inzuzo

Ngokukhawuleza
Fumana isiphumo ngaphakathi kwe-15 min, iintsuku ezi-3 ngaphambili kuneendlela zokubona eziqhelekileyo
Elula
Kulula ukuyisebenzisa, abasebenzi belabhoratri abaqhelekileyo banokusebenza ngaphandle koqeqesho
Ichanekile
Uvakalelo oluphezulu kunye neenkcukacha
Umda wokubona ophantsi: 0.20 ng / mL
Iyakwazi ukubona uninzi lwee-subtypes eziqhelekileyo ze-IMP

Isiphumo esiqondakalayo
Akukho mfuneko yokubala, iziphumo zokufunda ezibonwayo
Ezoqoqosho
Imveliso inokuthuthwa kwaye igcinwe kwiqondo lokushisa, ukunciphisa iindleko

Ukubaluleka kovavanyo lwe-CRE

Ngokudibeneyo, i-Enterobacterales lelona qela lixhaphakileyo leentsholongwane ezibangela usulelo olunxulumene nezempilo.Ezinye ze-Enterobacterales zinokuvelisa i-enzyme ebizwa ngokuba yi-carbapenemase eyenza i-antibiotics efana ne-carbapenems, i-penicillins, kunye ne-cephalosporins ingasebenzi.Ngenxa yesi sizathu, i-CRE iye yabizwa ngokuba “yi-nightmare bacteria” ngenxa yokuba kukho iindlela ezimbalwa zokubulala iintsholongwane, ukuba zikhona, ezishiyekileyo ukunyanga usulelo olubangelwa zezi ntsholongwane.

Iibhaktheriya ezivela kwintsapho ye-Enterobacterales, kuquka neentlobo ze-Klebsiella kunye ne-Escherichia coli, inokuvelisa i-carbapenemase.IiCarbapenemases zihlala ziveliswa kwimizila yemfuza ebekwe kwizinto ezidluliswayo ezinokusasaza ukuchasana ngokulula ukusuka kwintsholongwane ukuya kwintsholongwane kunye nomntu kumntu.Kwakhona ngenxa yokusetyenziswa kakubi kwamayeza okubulala iintsholongwane kunye neendlela ezilinganiselweyo ezithatyathiweyo ukuthintela ukusasazeka, ingxaki yeCRE eyanda ngendlela emangalisayo isisisongelo sobomi ehlabathini lonke.

Ngokwesiqhelo, ukusasazeka kwe-CRE kunokulawulwa ngolu hlobo:

Ukubeka iliso usulelo lwe-CRE
Zibeke zodwa izigulana ezine-CRE
Ukususa izixhobo zonyango ezihlaselayo ngaphakathi emzimbeni
Lumka xa umisela i-antibiotics (ingakumbi i-carbapenems)
Ukusebenzisa iindlela ezicocekileyo zokuthintela ukusasazeka kosulelo
Landela ngokungqongqo inkqubo yokucoca elebhu

……
Ukufunyanwa kwe-CRE kunexabiso elikhulu kulawulo lokusasazeka.Ngokuvavanya kwangethuba, ababoneleli bezempilo banokunika unyango olusengqiqweni ngakumbi kwizigulana ezisesichengeni se-CRE, kananjalo bafezekise ulawulo lwasesibhedlele.

IMP-uhlobo carbapenemase

I-Carbapenemase ibhekisela kuhlobo lwe-β-lactamase olunokuthi ubuncinane i-hydrolyze imipenem okanye i-meropenem, kuquka i-A, B, D iintlobo ezintathu ze-enzymes ezihlelwe yi-Ambler isakhiwo se-molecular.Phakathi kwabo, i-Class B i-metallo-β-lactamases (MBLs), kuquka i-carbapenemases efana ne-IMP, i-VIM kunye ne-NDM,.I-IMP-type carbapenemase, ekwaziwa njenge-impenemase metallo-beta-lactamase evelisa i-CRE, luhlobo oluxhaphake kakhulu lwee-MBL ezifunyenweyo kwaye isuka kudidi oluphantsi lwe-3A.Inokwenza i-hydrolyze phantse zonke ii-antibiotics ze-β-lactam.