I-Carbapenem-resistant OXA-48 Detection K-Set (Lateral Flow Assay) yinkqubo yokuvavanya i-immunochromatographic ejoliswe ekufumaneni umgangatho we-OXA-48-uhlobo lwe-carbapenemase kwiikholoni zebhaktheriya.Uvavanyo luvavanyo lwebhubhoratri yokusetyenziswa kwemithi enokuthi incede ekuxilongweni kwe-OXA-48-uhlobo lwe-carbapenem resistant strains.
Igama | I-Carbapenem-resistant OXA-48 Detection K-Set (I-Lateral Flow Assay) |
Indlela | I-Lateral Flow Assay |
Uhlobo lwesampuli | Iikholoni zebhaktheriya |
Inkcazo | Iimvavanyo ezingama-25/ikhithi |
Ixesha lokubona | 10-15 imiz |
Izinto zokubhaqa | Carbapenem-resistant Enterobacteriaceae (CRE) |
Uhlobo lokufunyanwa | OXA-48 |
Uzinzo | I-K-Set izinzile iminyaka emi-2 ku-2°C-30°C |
Ukubaluleka kovavanyo lwe-CRE
I-CRE, imele i-Enterobacteriaceae enganyangekiyo kwi-carbapenem, lusapho lweentsholongwane ekunzima ukuzinyanga ngenxa yokuba zixhathisa kakhulu kwiintsholongwane.Iintlobo zeKlebsiella kunye ne-Escherichia coli (E. coli) yimizekelo ye-Enterobacteriaceae, inxalenye eqhelekileyo yebhaktiriya yamathumbu omntu enokuthi ibe yi-carbapenem-resistant.Isizathu sokuba ii-CREs zixhathise kwi-carbapenems kukuba zivelisa i-carbapenemases.
Oogqirha badlala indima ebalulekileyo ekucutheni ukusasazeka kwe-CRE.Ngokwesiqhelo, banokunceda ukuthintela ukusasazeka kwe-CRE ngo
……
Ukuchonga ngokukhawuleza izigulane ezifakwe kwiikholoni okanye ezosulelwe kwezi zinto ziphilayo kwaye zibekwe kwiiNqaku zoQhagamshelwano xa kufanelekile, ukusebenzisa i-antibiotics ngobulumko, kunye nokunciphisa ukusetyenziswa kwesixhobo zonke iindawo ezibalulekileyo zokuthintela ukuhanjiswa kwe-CRE, oku kuthetha ukuba ukufunyanwa ngokukhawuleza nokuchanekileyo kwe-CRE kuyimfuneko kakhulu.
I-Carbapenemase ibhekisela kuhlobo lwe-β-lactamase olunokuthi ubuncinane i-hydrolyze imipenem okanye i-meropenem, kuquka i-A, B, D iintlobo ezintathu ze-enzymes ezihlelwe yi-Ambler isakhiwo se-molecular.Udidi D, olufana nohlobo lwe-OXA-uhlobo lwe-carbapenemase, lufunyenwe rhoqo kwi-Acinetobacteria.Uphononongo lokucupha lubonise ukuba i-OXA-48-type carbapenemases, ekwabizwa ngokuba yi-oxacillinase-48-like beta-lactamase, zezona carbapenemases zixhaphakileyo kwi-Enterobacterales kwimimandla ethile yehlabathi kwaye zingeniswa rhoqo kwimimandla yokungakhathali, apho banoxanduva lokuqhambuka kwe-nosocomial.
Umzekelo | Inkcazo | Ikhowudi yemveliso |
CPO48-01 | Iimvavanyo ezingama-25/ikhithi | CPO48-01 |