I-Carbapenem-resistant OXA-23 Detection K-Set (Lateral Flow Assay) yinkqubo yokuvavanya i-immunochromatographic ejoliswe ekufumaneni umgangatho we-OXA-23-uhlobo lwe-carbapenemase kwiikholoni zebhaktheriya.Uvavanyo luvavanyo lwebhubhoratri yokusetyenziswa kwemithi enokuthi incede ekuxilongweni kwe-OXA-23-uhlobo lwe-carbapenem resistant strains.
Igama | Carbapenem-resistant OXA-23 Detection K-Set (Lateral Flow Assay) |
Indlela | I-Lateral Flow Assay |
Uhlobo lwesampuli | Iikholoni zebhaktheriya |
Inkcazo | Iimvavanyo ezingama-25/ikhithi |
Ixesha lokubona | 10-15 imiz |
Izinto zokubhaqa | Carbapenem-resistant Enterobacteriaceae (CRE) |
Uhlobo lokufunyanwa | OXA-23 |
Uzinzo | I-K-Set izinzile iminyaka emi-2 ku-2°C-30°C |
I-CRE (i-Carbapenem-resistant Enterobacteriaceae) lusapho lweentsholongwane ekunzima ukuzinyanga ngenxa yokuba zixhathisa kakhulu kwii-antibiotics.Usulelo lwe-CRE luqhele ukwenzeka kwizigulana ezibhedlele, kumakhaya abantu abalupheleyo, nakwezinye iindawo zokhathalelo lwempilo.Izigulane ezikhathalelwayo zifuna izixhobo ezifana nezixhobo zokuphefumla (oomatshini bokuphefumla), ii-catheter zomchamo (isinyi), okanye ii-catheters zemithambo, kunye nezigulane ezithatha iikhosi ezinde zamayeza athile okubulala iintsholongwane zezona zisemngciphekweni wosulelo lwe-CRE.
Ezinye iintsholongwane ze-CRE ziye zaxhathisa kuninzi lwamayeza okubulala iintsholongwane akhoyo.Usulelo lwezi ntsholongwane kunzima kakhulu ukunyanga, kwaye lunokubulala-enye ingxelo ithi lunokuba negalelo ekufeni ukuya kuthi ga kwi-50% yezigulana ezosulelekileyo.
Ukuthintela ukusasazeka okuthe kratya kwe-CRE, kufuneka kubonelelwe ngokhathalelo lwempilo
……
Ukuchonga izigulane ezine-CRE ngokukhawuleza kwaye zibekwe zodwa kwezinye izigulana ze-ICU xa kufanelekile, ukusebenzisa amayeza okubulala iintsholongwane ngokufanelekileyo, kunye nokunciphisa ukusetyenziswa kwesixhobo esihlaselayo kubalulekile ekuthinteleni usulelo lwe-CRE.Uvavanyo olukhawulezileyo lwe-CRE luyimfuneko efunekayo ukuze kuphunyezwe ezi ndlela, nto leyo eyenza ukuba ibe yinxalenye ebalulekileyo yolawulo lweCRE yeklinikhi.
I-Carbapenemase ibhekisela kuhlobo lwe-β-lactamase olunokuthi ubuncinane i-hydrolyze imipenem okanye i-meropenem, kuquka i-A, B, D iintlobo ezintathu ze-enzymes ezihlelwe yi-Ambler isakhiwo se-molecular.Udidi D, olufana nohlobo lwe-OXA-uhlobo lwe-carbapenemase, lufunyenwe rhoqo kwi-Acinetobacteria.Kwiminyaka yakutshanje, kukho iingxelo zokulaliswa esibhedlele okubangelwa yi-OXA-23, okt Oxacillinase-23-like beta-lactamase.I-80% ye-carbapenem-resistant-resistant Acinetobacteria baumannii ivelisa i-OXA-23-type carbapenemase, eyenza ukuba unyango lwekliniki lube nzima kakhulu.
Umzekelo | Inkcazo | Ikhowudi yemveliso |
CPO23-01 | Iimvavanyo ezingama-25/ikhithi | CPO23-01 |