I-Carbapenem-resistant KPC Detection K-Set (Lateral Flow Assay) yinkqubo yovavanyo lwe-immunochromatographic eyenzelwe ukufumanisa umgangatho we-KPC-uhlobo lwe-carbapenemase kwiikholoni zebhaktiriya.Uvavanyo luvavanyo lwelabhoratri yokusetyenziswa kwemiyalelo enokuthi incede ekuxilongweni kohlobo lwe-KPC-uhlobo lwe-carbapenem oluxhathisayo.
Igama | Carbapenem-resistant KPC UFundo lwe-K-Seti (I-Lateral Flow Assay) |
Indlela | I-Lateral Flow Assay |
Uhlobo lwesampuli | Iikholoni zebhaktheriya |
Inkcazo | Iimvavanyo ezingama-25/ikhithi |
Ixesha lokubona | 10-15 imiz |
Izinto zokubhaqa | Carbapenem-resistant Enterobacteriaceae (CRE) |
Uhlobo lokufunyanwa | I-KPC |
Uzinzo | I-K-Set izinzile iminyaka emi-2 ku-2°C-30°C |
I-Carbapenem antibiotics yenye yezona ziyobisi zisebenzayo kulawulo lweklinikhi losulelo lwe-pathogenic.Izinto eziphilayo ezivelisa iCarbapenemase (CPO) kunye ne-carbapenem-resistant Enterobacter (CRE) ziye zaba ngumba wempilo yoluntu jikelele ngenxa yokunganyangeki kweziyobisi, kwaye ukhetho lonyango lwezigulane lulinganiselwe kakhulu.Abantu kwihlabathi liphela kufuneka banike ingqwalasela enkulu ekuthinteleni ukusasazeka kweCRE, ethi, ukuba ayipheleliselwanga, iya kuchaphazela ngokunzulu unyango lwezifo ezininzi, nto leyo eyenza kube nzima ukunyanga nokulawula izifo.
Ngokwesiqhelo, ababoneleli bezempilo banokunceda ukuthintela ukusasazeka kwe-CRE ngo
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Konke oku kubonisa ukubaluleka kokufunyanwa kwangoko kwe-CRE.Ukuvelisa iimveliso zoxilongo olukhawulezileyo kubaluleke kakhulu kuchwethezo lwangethuba lweentlobo ezinganyangekiyo ngamachiza, isikhokelo samayeza, kunye nokuphuculwa kwemigangatho yonyango kunye nempilo yabantu.
I-Carbapenemase ibhekisela kuhlobo lwe-β-lactamase olunokuthi ubuncinane i-hydrolyze imipenem okanye i-meropenem, kuquka i-A, B, D iintlobo ezintathu ze-enzymes ezihlelwe yi-Ambler isakhiwo se-molecular.Udidi A, olufana ne-KPC-uhlobo lwe-carbapenemase, lufunyenwe ngokukodwa kwiibhaktheriya ze-Enterobacteriaceae.I-Klebsiella pneumoniae carbapenemase, echazwe njenge-KPC, ibe yenye yezona ntsholongwane zibalulekileyo zangoku, ngelixa unyango olulolona luhlala lungachazwa.Usulelo ngenxa yee-KPCs lunxulunyaniswa nokusilela kunyango oluphezulu kunye namazinga okusweleka okungenani angama-50%.
Umzekelo | Inkcazo | Ikhowudi yemveliso |
I-CPK-01 | Iimvavanyo ezingama-25/ikhithi | I-CPK-01 |